DELAYED COLONOSCOPY AFTER FIT; REPEAT CROHN'S SURGERY; MICROBIOME AND PANCREATITIS

A delay of up to 2 years for follow-up colonoscopy after a positive fecal immunochemical test (FIT) was not associated with an increased risk of advanced adenoma, colorectal cancer (CRC), or advanced CRC, findings from a nationwide retrospective study in France suggested. (Gut)

In a cohort study that included long-term CRC survivors, several factors were associated with an increased risk of late-onset depression, including anxiety, female sex, Medicare/Medicaid dual eligibility, and a higher comorbidity burden. (JAMA Network Open)

Do surveillance guidelines need to account for the fact that the use of artificial intelligence in colonoscopy often reclassifies low-risk patients as high-risk due to increased detection of primarily nonadvanced adenomas? (Gastroenterology)

Ulcerative colitis patients who discontinued 5-aminosalicylic acid (5-ASA) monotherapy have an increased risk of relapse, according to a meta-analysis, though 5-ASA discontinuation may be feasible in ulcerative colitis or Crohn's disease patients who are also on immunomodulators or biologics. (Inflammatory Bowel Diseases)

In the biologics era, 4.5% of patients who underwent ileocolic anastomosis for Crohn's disease required repeat surgeries for recurrence at that initial site at 5 years, increasing to 12.8% at 10 years, a large Australian cohort study found. (Inflammatory Bowel Diseases)

In a database study of more than 15,000 inflammatory bowel disease patients, treatment response lasting at least a year after starting a first advanced therapy was linked to a lower long-term risk of hospitalization. (Inflammatory Bowel Diseases)

Authors in Lancet Gastroenterology & Hepatology reviewed the therapeutic landscape for metabolic dysfunction-associated steatohepatitis, while the American Journal of Gastroenterology reviewed barriers and facilitators of getting treatment for alcohol addiction and Gastroenterology reviewed the role of alcohol in pancreatic diseases.

An analysis of U.K. Biobank data detailed the contributions of alcohol consumption and cardiometabolic risk factors to liver-related events. (Hepatology)

For veterans with cirrhosis, having a mental health condition was linked to an increased risk of liver cancer, a retrospective study found. (Clinical Gastroenterology and Hepatology)

Using buccal and rectal swabs, researchers found that the microbiome of acute pancreatitis patients at the time of hospitalization correlated with diabetes risk post-discharge. (Gut)

2025-12-04T22:59:35Z